Tag: pcr

Mass PCR testing is creating a casedemic, that is, a pandemic of allegedly Covid-positive people, the overwhelming majority of which isn’t actually ill.

There are four main factors contributing to poor performance of PCR testing:

1. Low prevalence of disease. This is the case in the UK and most of Europe. «When virus levels in the population are very low, the chances of a test accurately detecting Covid-19 could be even less than 50 per cent»

2. High cycle threshold. The PCR test amplifies genetic matter from the virus in cycles; the fewer cycles required, the greater the amount of virus, or viral load, in the sample. The greater the viral load, the more likely the patient is to be contagious. This number of amplification cycles needed to find the virus, called the cycle threshold, is never included in the results sent to doctors and coronavirus patients, although it could tell them how infectious the patients are. Any test with a cycle threshold above 35 is too sensitive, and yet most Covid-19 tests have a CT of 40, with some with a CT as high as 47, and just few with a CT of 37. In Massachusetts, from 85 to 90 percent of people who tested positive in July with a cycle threshold of 40 would have been deemed negative if the threshold were 30 cycles. This was observed and published about already in May: Predicting Infectious Severe Acute Respiratory Syndrome Coronavirus 2 From Diagnostic Samples.

3. Cross T-cell immunity. There’s mounting evidence of cross T-cell immunity for coronaviruses, meaning that even exposure to common cold viruses (these, too, are coronaviruses) trains the immune system to respond to more dangerous coronaviruses (SARS 1 and 2, MERS). See, amongst others:

• Nasal priming by a murine coronavirus provides protective immunity against lethal heterologous virus pneumonia
• Clinical, immunological and virological characterization of COVID-19 patients that test re-positive for SARS-CoV-2 by RT-PCR
• The impact of host resistance on cumulative mortality and the threshold of herd immunity for SARS-CoV-2
• Presence of SARS-CoV-2 reactive T cells in COVID-19 patients and healthy donors

4. Lack of specific RNA sequences required by testing. There is no guidance providing details on the specific RNA sequences required by testing, a threshold for the test result and the need for confirmatory testing. It is therefore not clear what constitutes a positive result.

All this is creating a wave of cases, which in most part are people who are not actually sick. The pandemic seems to be over, and it also seems that many don’t want it to be.

This is clear from WHO guidance on what constitutes a positive case, which are pretty much followed in most of the western world:

• A suspect case has clinical symptoms of respiratory disease, perhaps with other associated presentations. 
• A probable case is a suspect case for whom laboratory testing was inconclusive or not possible. 
• A confirmed case is “A person with laboratory confirmation of COVID-19 infection, irrespective of clinical signs and symptoms.” 

Notice how suspect and probable rely on a broader clinical picture, whereas the confirmed relies solely on the PCR test, irrespective of clinical signs and symptoms. This is very bad, since asymptomatic people are by and large not actually ill. This is why:

The one thing historically people need to realise [is] that even if there is some asymptomatic transmission, in all the history of respiratory-borne viruses of any type, asymptomatic transmission has never been the driver of outbreaks. The driver of outbreaks is always a symptomatic person. Even if there is a rare asymptomatic person that might transmit, an epidemic is not driven by asymptomatic carriers.

Dr ANthony Fauci